Optimal dosing of high-dose melphalan prior to autologous hematopoietic stem cell transplantation in a patient with AL amyloidosis and a solitary kidney.
نویسندگان
چکیده
http://dx.doi.org/10.1016/j.hemonc.2015.08.001 1658-3876/ 2015 King Faisal Specialist Hospital & Research Centre. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). * Corresponding author at: Boston Medical Center, 820 Harrison Avenue, FGH-1007, Boston, MA 02118, USA. Tel.: +1 617 638 7002; fax: +1 617 414 1831. E-mail address: [email protected] (V. Sanchorawala). Shin Yin Lee , Dina Brauneis , Lauren Stern , Vaishali Sanchorawala a,b,*
منابع مشابه
High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis.
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متن کاملHepatic response after high-dose melphalan and stem cell transplantation in patients with AL amyloidosis associated liver disease.
High-dose melphalan chemotherapy and autologous peripheral blood stem cell transplantation has been shown to result in durable hematologic response and prolonged overall survival in systemic AL amyloidosis. In this retrospective study, we evaluated clinical and hematologic responses in 69 patients with predominant liver involvement who were treated with high-dose intravenous melphalan and autol...
متن کاملHigh-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study.
BACKGROUND AL amyloidosis is a fatal disease resulting from tissue deposition of amyloid fibrils derived from monoclonal immunoglobulin light chains. Treatment with oral chemotherapy is minimally effective. OBJECTIVE To test survival and organ response in a large sample of patients treated with high-dose intravenous melphalan (100 to 200 mg/m2) and autologous blood stem-cell transplantation. ...
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ورودعنوان ژورنال:
- Hematology/oncology and stem cell therapy
دوره 9 2 شماره
صفحات -
تاریخ انتشار 2016